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Exclusion criteria Participants with severe heart, brain, lung-related system diseases, and diabetes were excluded, along with those who received other relevant smoking cessation treatment in the past 2 weeks

Aim to drink at least 2 litres of water a day

Vaping is often seen as a safer alternative due to the absence of combustion and tar

Ex vivo patch-clamp recordings of VTA DA neurons To verify the functional expression of the excitatory opsin CatCh and the inhibitory opsin Jaws, 1012 weeks-old male DAT iCRE mice were injected with the viruses described above

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